Michael Riehle's Lab
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The Riehle Lab:
Mosquito Research at the University of Arizona

Performing cutting edge research on mosquito physiology to control mosquito-borne diseases and improve human health

Welcome to our lab

Mosquito borne diseases, such as malaria, lymphatic filariasis, and dengue virus, sicken and kill millions of people every year.  We are interested in developing new strategies for controlling mosquitoes and the diseases they transmit.  Specifically,  we are attempting to understand the basic molecular mechanisms regulating reproduction, innate immunity, metabolism and lifespan in the mosquito.  We are also interested in understanding the ecology the mosquito Aedes aegypti, the primary vector of dengue, Zika and Chikungunya viruses, that represent a possible risk to Arizona. 

Current Projects:
  • Explore how Coenzyme A biosynthesis can be manipulated in Anopheles mosquitoes to limit malaria parasite development.
  • Studying and disrupting the mosquito larval midgut using novel pH responsive probes.
  • Manipulate the insulin signaling pathway to improve innate immunity and impact mosquito fitness.
  • Develop methods for assessing the population age structure of Ae. aegypti mosquitoes in Southern Arizona using parity, transcript expression and NIRS.  
Female Ae. aegypti mosquito in flight

Dr. michael riehle

Department of Entomology
University of Arizona
Forbes 410
1140 E. South Campus Dr.
Tucson, AZ, 85721-0036
Phone: 520-626-8500
Email: [email protected]

Additional information on Michael Riehle
Department Website : BIO5 Website
Researchgate : Google Scholar : Loop : SciProfiles

Lab news and updates

Recent publications:
Isoe, J., Riske, B.F., Dobson, M.E., Kaylor, H.L., Brady, J.C., Debebe, Y., Saavedra, L.M., Luckhart, S. and Riehle, M.A. Characterization of the Sodium Multi-Vitamin Transporter in the Mosquito Anopheles stephensi and Its Capacity to Mobilize Pantothenate and Biotin. Biomolecules, 15(1), p.59. (2025)

Guzmán L, Wijetunge AN, Riske BF, Massani BB, Riehle MA, Jewett JC. Chemical probes to interrogate the extreme environment of mosquito larvae guts. Journal of the American Chemical Society. (2024)


In the news:
The Scientist: Gut-powered mosquito probes
Malaria Eradication Scientific Alliance (MESA) - October 2024 newsletter

Monsoon storms bring out more mosquitoes
3 cheap and easy ways to make a DIY mosquito trap
UA scientists explore new way to control mosquito populations
Innovative chemical strategy targets mosquito larvae gut to combat spread of deadly diseases

Riehle Labs - Seeing Double
4 cases of West Nile virus reported in the Valley. What to expect this summer

UI prof gets grant to study malaria
Mosquito season in metro Phoenix: How bad is the summer of 2022 likely to be?
West Nile virus spikes in Arizona
Mosquitos biting their way through Southern Arizona
What’s up with all the flies and mosquitoes?
Monsoon mosquitoes
​Why do mosquitoes buzz in our ears?
2020 MCB Galileo Circle Scholarship winner is Lillian Delacruz!
NPR : Deconstructing dengue
UA re-engineering mosquitoes to resist disease


Videos from the riehle laB

Life cycle of the Yellow Fever mosquito Aedes aegypti
Michael Riehle youtube mosquito life cycle
Introduction to our work
Michael Riehle youtube research background

Affiliations

Biology of Disease Vectors Course
Insects Journal - MDPI - Michael Riehle editorial board member

Riehle Lab INfo

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  • Home
  • Current Research
  • Publications
  • Lab Members
    • Jun Isoe
    • Frank Ramberg
    • Brendan Riske
    • Jenet Shoumaker Soto
    • Ava Bartlett-Miller
  • Prospective Students
  • Collaborators
  • Sponsors
  • About Me
  • The Riehle Lab Blog