Michael Riehle's Lab
  • Home
  • Current Research
  • Publications
  • Lab Members
    • Minhao Chen
    • Jun Isoe
    • Frank Ramberg
    • Brendan Riske
    • Jenet Soto-Shoumaker
  • Prospective Students
  • Collaborators
  • Sponsors
  • About Me
  • The Riehle Lab Blog

The Riehle Lab:
Mosquito Research at the University of Arizona

Performing cutting edge research on mosquito physiology to control mosquito-borne diseases and improve human health

Welcome to our lab

Mosquito borne diseases, such as malaria, lymphatic filariasis, and dengue virus, sicken and kill millions of people every year.  We are interested in developing new strategies for controlling mosquitoes and the diseases they transmit.  Specifically,  we are attempting to understand the basic molecular mechanisms regulating reproduction, innate immunity, metabolism and lifespan in the mosquito.  We are also interested in understanding the ecology the mosquito Aedes aegypti, the primary vector of dengue, Zika and Chikungunya viruses, that represent a possible risk to Arizona. 

Current Projects:
  • Explore how Coenzyme A biosynthesis can be manipulated in Anopheles mosquitoes to limit malaria parasite development.
  • Explore the physiological roles of distinct insulin-like peptides in mosquitoes using CRISPR/Cas9.
  • Manipulate the insulin signaling pathway to improve innate immunity and impact mosquito fitness.
  • Develop methods for assessing the population age structure of Ae. aegypti mosquitoes in Southern Arizona using parity, transcript expression and NIRS.  
Female Ae. aegypti mosquito in flight

Dr. michael riehle

Department of Entomology
University of Arizona
Forbes 410
1140 E. South Campus Dr.
Tucson, AZ, 85721-0036
Phone: 520-626-8500
Email: mriehle@ag.arizona.edu

Additional information on Michael Riehle
Department Website : BIO5 Website
Researchgate : Google Scholar : Loop : SciProfiles

Lab news and updates

Recent publications:
Joy T, Chen M, Arnbrister J, Williamson D, Li S, Nair S, Brophy M, Garcia VM, Walker K, Ernst K, Gouge DH, Carrière Y, Riehle MA. Assessing Near-Infrared Spectroscopy (NIRS) for Evaluation of Aedes aegypti Population Age Structure. Insects. 2022; 13(4):360.

Brophy M, Riehle MA, Mastrud N, Ravenscraft A, Adamson JE, Walker KR. Genetic Variation in Rhipicephalus sanguineus s.l. Ticks across Arizona. Int. J. Environ. Res. Public Health. 19, 4223. (2022)

Hun LV, Cheung KW, Brooks E, Zudekoff R, Luckhart S, Riehle MA. Increased insulin signaling in the Anopheles stephensi fat body regulates metabolism and enhances the host response to both bacterial challenge and Plasmodium falciparum infection. Insect Biochemistry and Molecular Biology. (2021)

Simão-Gurge RM, Thakre N, Strickland J, Isoe J, Delacruz LR, Torrevillas BK, Rodriguez AM, Riehle MA, & Luckhart S. Activation of Anopheles stephensi pantothenate kinase and coenzyme A biosynthesis reduces infection with diverse Plasmodium species in the mosquito host. Biomolecules. (2021)

Oringanje, C., Delacruz, LR., Han, Y., Luckhart, S., & Riehle, MA. Overexpression of activated AMPK in the Anopheles stephensi midgut impacts mosquito metabolism, reproduction and Plasmodium resistance. Genes, 12(1), 119. (2021)

In the news:

Mosquito season in metro Phoenix: How bad is the summer of 2022 likely to be?
West Nile virus spikes in Arizona
Mosquitos biting their way through Southern Arizona
What’s up with all the flies and mosquitoes?
Monsoon mosquitoes
​Why do mosquitoes buzz in our ears?
2020 MCB Galileo Circle Scholarship winner is Lillian Delacruz!
Zika research at UA
NPR : Deconstructing dengue
UA re-engineering mosquitoes to resist disease


Videos from the riehle laB

Life cycle of the Yellow Fever mosquito Aedes aegypti
Michael Riehle youtube mosquito life cycle
Introduction to our work
Michael Riehle youtube research background

Affiliations

Biology of Disease Vectors Course
Insects Journal - MDPI - Michael Riehle editorial board member
Molecular Insect Science meeting - Michael Riehle organizer

Riehle Lab INfo

About
Research
People
Joining us
Picture
Picture
  • Home
  • Current Research
  • Publications
  • Lab Members
    • Minhao Chen
    • Jun Isoe
    • Frank Ramberg
    • Brendan Riske
    • Jenet Soto-Shoumaker
  • Prospective Students
  • Collaborators
  • Sponsors
  • About Me
  • The Riehle Lab Blog