Michael Riehle's Lab
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The Riehle Lab:
Mosquito Research at the University of Arizona

Performing cutting edge research on mosquito physiology to control mosquito-borne diseases and improve human health

Welcome to our lab

Mosquito borne diseases, such as malaria, lymphatic filariasis, and dengue virus, sicken and kill millions of people every year.  We are interested in developing new strategies for controlling mosquitoes and the diseases they transmit.  Specifically,  we are attempting to understand the basic molecular mechanisms regulating reproduction, innate immunity, metabolism and lifespan in the mosquito.  We are also interested in understanding the ecology the mosquito Aedes aegypti, the primary vector of dengue, Zika and Chikungunya viruses, that represent a possible risk to Arizona. 

Current Projects:
  • Explore how Coenzyme A biosynthesis can be manipulated in Anopheles mosquitoes to limit malaria parasite development.
  • Explore the physiological roles of distinct insulin-like peptides in mosquitoes using CRISPR/Cas9.
  • Manipulate the insulin signaling pathway to improve innate immunity and impact mosquito fitness.
  • Develop methods for assessing the population age structure of Ae. aegypti mosquitoes in Southern Arizona using parity, transcript expression and NIRS.  
Female Ae. aegypti mosquito in flight

Dr. michael riehle

Department of Entomology
University of Arizona
Forbes 410
1140 E. South Campus Dr.
Tucson, AZ, 85721-0036
Phone: 520-626-8500
Email: mriehle@ag.arizona.edu

Additional information on Michael Riehle
Department Website : BIO5 Website
Researchgate : Google Scholar : Loop : SciProfiles

Lab news and updates

Recent publications:
Ernst KC, Walker KR, Castro-Luque AL, Schmidt C, Joy TK, Brophy M, Reyes-Castro P, Díaz-Caravantes RE, Encinas VO, Aguilera A, Gameros M, Cuevas Ruiz RE, Hayden MH, Alvarez G, Monaghan A, Williamson D, Arnbrister J, Gutiérrez EJ, Carrière Y, Riehle MA. Differences in Longevity and Temperature-Driven Extrinsic Incubation Period Correlate with Varying Dengue Risk in the Arizona–Sonora Desert Region. Viruses. 15(4):851. (2023)

Gutiérrez EH, Riehle MA, Walker KR, Ernst KC, Davidowitz G. Using body size as an indicator for age structure in field populations of Aedes aegypti (Diptera: Culicidae). Parasites & Vectors. 15(1): 1-5. (2022)

Thakre N, Gurge RM, Isoe J, Kivi H, Strickland J, Delacruz LR, Rodriguez AM, Haney R, Sadeghi R, Joy T, Chen M, Luckhart S, Riehle MA. Manipulation of pantothenate kinase in Anopheles stephensi suppresses pantothenate levels with minimal impacts on mosquito fitness. Insect Biochemistry and Molecular Biology. 149 (2022)

Joy T, Chen M, Arnbrister J, Williamson D, Li S, Nair S, Brophy M, Garcia VM, Walker K, Ernst K, Gouge DH, Carrière Y, Riehle MA. Assessing Near-Infrared Spectroscopy (NIRS) for Evaluation of Aedes aegypti Population Age Structure. Insects. 13(4):360. (2022)   

Brophy M, Riehle MA, Mastrud N, Ravenscraft A, Adamson JE, Walker KR. Genetic Variation in Rhipicephalus sanguineus s.l. Ticks across Arizona. Int. J. Environ. Res. Public Health. 19, 4223. (2022)

In the news:
Mosquito season in metro Phoenix: How bad is the summer of 2022 likely to be?
West Nile virus spikes in Arizona
Mosquitos biting their way through Southern Arizona
What’s up with all the flies and mosquitoes?
Monsoon mosquitoes
​Why do mosquitoes buzz in our ears?
2020 MCB Galileo Circle Scholarship winner is Lillian Delacruz!
Zika research at UA
NPR : Deconstructing dengue
UA re-engineering mosquitoes to resist disease


Videos from the riehle laB

Life cycle of the Yellow Fever mosquito Aedes aegypti
Michael Riehle youtube mosquito life cycle
Introduction to our work
Michael Riehle youtube research background

Affiliations

Biology of Disease Vectors Course
Insects Journal - MDPI - Michael Riehle editorial board member
Molecular Insect Science meeting - Michael Riehle organizer

Riehle Lab INfo

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  • Home
  • Current Research
  • Publications
  • Lab Members
    • Jun Isoe
    • Frank Ramberg
    • Brendan Riske
    • Jenet Shoumaker Soto
  • Prospective Students
  • Collaborators
  • Sponsors
  • About Me
  • The Riehle Lab Blog